| Scarlet Soldier's Waistguard | Blacksmithing | 250 | — | not recorded |
Scorpid Sample | — | ? | Acceptable Scorpid Sample | Untested Scorpid Sample |
Scorpid Surprise | Cooking | 20 | Scorpid Surprise | Recipe: Scorpid Surprise |
| Scraping | — | ? | — | not recorded |
Scroll of Spatial Mending | Enchanting | 120 | Scroll of Spatial Mending | not recorded |
| Scroll: Wrath of the Swarm | Enchanting | 300 | — | not recorded |
| Seal Felvine Shard | — | ? | — | Reliquary of Purity |
Searing Golden Blade | Blacksmithing | 190 | Searing Golden Blade | Plans: Searing Golden Blade |
Seasoned Wolf Kabob | Cooking | 100 | Seasoned Wolf Kabob | Recipe: Seasoned Wolf Kabob |
Sebacious Poison | Poisons | 300 | Sebacious Poison | not recorded |
| Semisafe Transporter: New Avalon | Engineering | 300 | — | not recorded |
Serenity | Blacksmithing | 285 | Serenity | Plans: Serenity |
Shadow Crescent Axe | Blacksmithing | 200 | Shadow Crescent Axe | Plans: Shadow Crescent Axe |
Shadoweave Boots | Tailoring | 240 | Shadoweave Boots | 2 trainers |
Shadoweave Gloves | Tailoring | 225 | Shadoweave Gloves | 2 trainers |
Shadoweave Mask | Tailoring | 245 | Shadoweave Mask | Pattern: Shadoweave Mask |
Shadoweave Pants | Tailoring | 210 | Shadoweave Pants | 2 trainers |
Shadoweave Robe | Tailoring | 215 | Shadoweave Robe | 2 trainers |
Shadoweave Shoulders | Tailoring | 235 | Shadoweave Shoulders | 2 trainers |
Shadow Goggles | Engineering | 120 | Shadow Goggles | Schematic: Shadow Goggles |
| Shadow Guard | — | ? | — | Shadow Guard |
Shadow Hood | Tailoring | 170 | Shadow Hood | Pattern: Shadow Hood |
| Shadow Mantle of the Dawn | — | ? | — | Shadow Mantle of the Dawn |
Shadow Oil | Alchemy | 165 | Shadow Oil | Recipe: Shadow Oil |
Shadow Protection Potion | Alchemy | 135 | Shadow Protection Potion | Recipe: Shadow Protection Potion |
Shadowskin Gloves | Leatherworking | 200 | Shadowskin Gloves | Pattern: Shadowskin Gloves |
| Sharpened Chitin Armor Kit | Leatherworking | 300 | — | not recorded |
Shifting Cloak | Leatherworking | 300 | Shifting Cloak | Pattern: Shifting Cloak |
Shining Silver Breastplate | Blacksmithing | 135 | Shining Silver Breastplate | 10 trainers |
| Shoulderpads of Obsession | Leatherworking | 250 | — | not recorded |
| Shoulderpads of the Deranged | Tailoring | 250 | — | not recorded |
| Shoulderplates of Dread | Blacksmithing | 250 | — | not recorded |
| Shrieking Spaulders | Leatherworking | 250 | — | not recorded |
Sigil of Flowing Waters | Enchanting | 290 | Enchanted Sigil: Flowing Waters | not recorded |
Sigil of Innovation | Enchanting | 225 | Enchanted Sigil: Innovation | not recorded |
| Sigil of Living Dreams | Enchanting | 250 | — | not recorded |
| Signing | — | ? | — | Nixx's Pledge of Secrecy |
| Signing | — | ? | — | Oglethorpe's Pledge of Secrecy |
| Signing | — | ? | — | Overspark's Pledge of Secrecy |
Silk Bandage | First aid | 150 | Silk Bandage | 13 trainers |
Silk Headband | Tailoring | 160 | Silk Headband | 5 trainers |
Silver Contact | Engineering | 90 | Silver Contact | 8 trainers |
Silvered Bronze Boots | Blacksmithing | 130 | Silvered Bronze Boots | 10 trainers |
Silvered Bronze Breastplate | Blacksmithing | 130 | Silvered Bronze Breastplate | Plans: Silvered Bronze Breastplate |
Silvered Bronze Gauntlets | Blacksmithing | 135 | Silvered Bronze Gauntlets | 10 trainers |
Silvered Bronze Leggings | Blacksmithing | 155 | Silvered Bronze Leggings | Plans: Silvered Bronze Leggings |
Silvered Bronze Shoulders | Blacksmithing | 125 | Silvered Bronze Shoulders | Plans: Silvered Bronze Shoulders |
Silver-plated Shotgun | Engineering | 130 | Silver-plated Shotgun | 8 trainers |
Silver Rod | Blacksmithing | 100 | Silver Rod | 10 trainers |
Silver Skeleton Key | Blacksmithing | 100 | Silver Skeleton Key | 7 trainers |